Gut Microbiome in Down Syndrome

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Gut Microbiome in Down Syndrome

BACKGROUND Premature aging seriously compromises the health status of Down Syndrome (DS) persons. Since human aging has been associated with a deterioration of the gut microbiota (GM)-host mutualism, here we investigated the composition of GM in DS. METHODS The observational study presented involved 17 adult DS persons. We characterized the GM structure by 454 pyrosequencing of the V4 region ...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0112023